SCHEMBL83598

SCHEMBL83598

C=CCC1(c2ccccc2)CO1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.41
LMNA P02545 2/20 0.38
GAA P10253 1/20 0.38
HSD11B1 P28845 1/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
KMT2A Q03164 1/20 0.36
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
DPP4 P27487 1/20 0.34
HTR1A P08908 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL6436020 0.98 EGFR (0.40) EGFRLMNAGAAHSD11B1MEN1
Sulfuric Acid SCHEMBL8520420 0.88 EGFR (0.38) EGFRLMNAGAAHSD11B1MEN1
SCHEMBL24565312 0.79 EGFR (0.49) EGFRLMNAGAAHSD11B1MEN1
SCHEMBL22323612 0.79 EGFR (0.49) EGFRLMNAGAAHSD11B1MEN1
SCHEMBL433316 0.79 MEN1 (0.40) EGFRHSD11B1MEN1ALDH1A1POLB
SCHEMBL9449399 0.77 EGFR (0.34) EGFRLMNAGAAHSD11B1MEN1
SCHEMBL2764548 0.72 HTR1A (0.39) EGFRTSHRMAPK1SMN1; SMN2L3MBTL1
SCHEMBL6493726 0.72 MEN1 (0.40) EGFRMEN1POLBKMT2ATSHR
SCHEMBL8951708 0.72 GAA (0.39) EGFRLMNAGAAALDH1A1TSHR
SCHEMBL6493723 0.72 MEN1 (0.40) EGFRMEN1POLBKMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1790643-B1 QUINUCLIDINE COMPOUNDS HAVING QUATERNARY AMMONIUM GROUP, IT'S PREPARATION METHOD AND USE AS BLOCKING AGENTS OF ACETYCHOLINE ZHAO SHUQIANG (CN) 2010-06-02 EP claimed
US-7521559-B2 Quinuclidine compounds having quaternary ammonium group, its preparation method and use as blocking agents of acetylcholine Zhao, Shuqiang (CN) 2009-04-21 US claimed
US-20080247963-A1 Quinuclidine Compounds Having Quaternary Ammonium Group, Its Preparation Method and Use as Blocking Agents of Acetylcholine Zhao, Shuqiang (CN) 2008-10-09 US claimed
EP-1790643-A1 QUINUCLIDINE COMPOUNDS HAVING QUATERNARY AMMONIUM GROUP, IT'S PREPARATION METHOD AND USE AS BLOCKING AGENTS OF ACETYCHOLINE Zhao, Shuqiang (CN) 2007-05-30 EP claimed
EP-0425463-B1 Lavatory cleansing and sanitizing composition KIWI BRANDS INC (US) 1996-01-10 EP claimed
US-5344811-A Water solubility, surfactants KIWI BRANDS INC (US) 1994-09-06 US claimed
US-4060433-A Foam phosphatizing method and composition ECONOMICS LABORATORY, INC. (US) 1977-11-29 US claimed
JP-2153350-A None JP disclosed
JP-2107616-A None JP disclosed
WO-2024120763-A1 LITHOGRAPHIC PRINTING PRESS MAKE-READY METHOD ECO3 BV (BE) 2024-06-13 WO disclosed
EP-4382306-A1 LITHOGRAPHIC PRINTING PRESS MAKE-READY METHOD ECO3 BV (BE) 2024-06-12 EP disclosed
CN-112912798-B Lithographic printing plate precursor 易客发有限公司 2024-03-29 CN disclosed
US-20240100820-A1 Lithographic Printing Press Make-Ready Method AGFA OFFSET BV (BE) 2024-03-28 US disclosed
US-4115105-A FRUIT RIPENING AND ABSCISSION AGENT HOFFMANN-LA ROCHE INC. (US) 1978-09-19 US disclosed
US-4107054-A NATURAL OR SYNTHETIC LUBRICANT - ALKENYLSUCCINIMIDE DISPERSANT - ANTHRANILIC ACID, ALKYLBENZOIC ACID, OR ALKYLCATECHOL AS RUST INHIBITOR CONTINENTAL OIL COMPANY (US) 1978-08-15 US disclosed
US-4088778-A VITAMIN E DERIVATIVE EISAI CO., LTD. (JA) 1978-05-09 US disclosed
US-4073995-A 2-ACRYLAMIDO-2-METHYLPROPANE SULFONIC ACID MONSANTO COMPANY (US) 1978-02-14 US disclosed
US-4073994-A 2-ACRYLAMIDO-2-METHYLPROPANE SULFONIC ACID COMONOMER MONSANTO COMPANY (US) 1978-02-14 US disclosed
US-3947437-A Substituted pyridazinyloxy(thio)phenyl ureas and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1976-03-30 US disclosed
US-3716547-A PROCESS FOR THE PREPARATION OF A POLY(VINYL ACETATE-DIALKYL MALEAEE-ACRYLIC ACID) TEXTILE SIZES MONSANTO CO 1973-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080247963-A1 Quinuclidine Compounds Having Quaternary Ammonium Group, Its Preparation Method and Use as Blocking Agents of Acetylcholine CHRM1, CHRNA1, CHRM2 EGFR 675/4885LMNA 2508/4885GAA 2436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.