Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10733404 | 0.86 | LMNA (0.64) | LMNACYP1A2CYP2D6MAPTL3MBTL1 | |
| SCHEMBL8361658 | 0.85 | MAPT (0.65) | LMNACYP1A2CYP2D6MAPTL3MBTL1 | |
| SCHEMBL8361515 | 0.84 | LMNA (0.61) | LMNACYP1A2CYP2D6MAPTL3MBTL1 | |
| SCHEMBL8357469 | 0.83 | MAPT (0.60) | LMNACYP1A2CYP2D6MAPTL3MBTL1 | |
| SCHEMBL8361433 | 0.83 | LMNA (0.59) | LMNACYP1A2CYP2D6MAPTL3MBTL1 | |
| SCHEMBL8359753 | 0.82 | LMNA (0.64) | LMNACYP1A2CYP2D6MAPTL3MBTL1 | |
| SCHEMBL8355843 | 0.82 | LMNA (0.58) | LMNACYP1A2CYP2D6MAPTL3MBTL1 | |
| SCHEMBL8355890 | 0.81 | MAPT (0.61) | LMNACYP1A2CYP2D6MAPTL3MBTL1 | |
| SCHEMBL8361580 | 0.80 | LMNA (0.61) | LMNACYP1A2CYP2D6MAPTL3MBTL1 | |
| SCHEMBL8361980 | 0.79 | LMNA (0.55) | LMNACYP1A2CYP2D6MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919807-A | ANTICHOLESTEROL AGENTS | DR. KARL THOMAE GMBH (DE) | 1999-07-06 | — | — | US | disclosed |
| EP-0824529-A1 | BENZOTHIAZOLES AND BENZOXAZOLES, AS WELL AS DRUGS CONTAINING THEM, THEIR USE AND METHODS OF PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035681-A1 | BENZOTHIAZOLES AND BENZOXAZOLES, AS WELL AS DRUGS CONTAINING THEM, THEIR USE AND METHODS OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-11-14 | — | — | WO | disclosed |