⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44968 | 0.86 | — | — | |
| SCHEMBL24866428 | 0.84 | AKT2 (0.44) | — | |
| SCHEMBL21263656 | 0.81 | NOS2 (0.44) | — | |
| SCHEMBL11588923 | 0.78 | — | — | |
| SCHEMBL32670416 | 0.78 | — | — | |
| SCHEMBL292535 | 0.78 | — | — | |
| SCHEMBL4630135 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL7822843 | 0.77 | AKT2 (0.40) | — | |
| SCHEMBL458851 | 0.77 | TDP1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL11590343 | 0.77 | AKT2 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240101531-A1 | PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | XENON PHARMACEUTICALS INC. (CA) | 2024-03-28 | — | — | US | disclosed |
| EP-2272848-B1 | Xanthine derivatives as selective HM74A agonists | GLAXOSMITHKLINE LLC (US) | 2012-12-26 | — | — | EP | disclosed |
| US-8143264-B2 | Xanthine derivatives as selective HM74A agonists | GLAXOSMITHKLINE LLC (US) | 2012-03-27 | — | — | US | disclosed |
| US-20110257205-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | GLAXOSMITHKLINE LLC | 2011-10-20 | — | — | US | disclosed |
| EP-2272848-A1 | Xanthine derivatives as selective HM74A agonists | Glaxosmithkline LLC (US) | 2011-01-12 | — | — | EP | disclosed |
| US-20100179128-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | SMITHKLINE BEECHAM CORPORATION | 2010-07-15 | — | — | US | disclosed |
| US-20100168122-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-07-01 | — | — | US | disclosed |
| EP-1912991-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | SmithKline Beecham Corporation (US) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017261-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-02-15 | — | — | WO | disclosed |
| US-5753715-A | 2-disubstituted cyclohexenyl and cyclohexyl antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |
| WO-1997048675-A1 | 2-DISUBSTITUTED CYCLOHEXENYL AND CYCLOHEXYL ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-24 | — | — | WO | disclosed |
| US-5151356-A | Yellow dye forming polymer couplers and dye developers | FUJI PHOTO FILM CO., LTD. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0495251-A1 | Local communication system and frame forming comprising a programmable address generator for such a system | Koninklijke Philips Electronics N.V. (NL) | 1992-07-22 | — | — | EP | disclosed |
| EP-0259864-B1 | SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1991-09-04 | — | — | EP | disclosed |
| EP-0259864-A2 | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1988-03-16 | — | — | EP | disclosed |
| US-4522916-A | MAGENTA IMAGE-FORMING POLYMER COUPLER LATEX; IMPROVED GRANULARITY | FUJI PHOTO FILM CO., LTD. (JP) | 1985-06-11 | — | — | US | disclosed |
| US-4111751-A | PYRAZOLE IMMOBILIZED ON A SOLID INSOLUBLE SUPPORT | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1978-09-05 | — | — | US | disclosed |