Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 12/20 | 0.51 |
| ▸ | F3 | P13726 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645944 | 0.90 | F7 (0.47) | F7F3ALDH1A1JAK2JAK1 | |
| SCHEMBL8363690 | 0.89 | MEN1 (0.42) | F7F3ALDH1A1GAAMAPT | |
| SCHEMBL8360311 | 0.89 | F7 (0.40) | F7F3ALDH1A1GAAMAPT | |
| SCHEMBL6797704 | 0.88 | F7 (0.41) | F7F3ALDH1A1GAAHPGD | |
| SCHEMBL8363659 | 0.84 | F7 (0.47) | F7F3GAAMAPT | |
| SCHEMBL6791991 | 0.83 | F7 (0.44) | F7F3ALDH1A1GAAHPGD | |
| SCHEMBL6791974 | 0.83 | F7 (0.44) | F7F3ALDH1A1GAAHPGD | |
| SCHEMBL6794526 | 0.79 | F7 (0.44) | F7F3GAAMAPT | |
| SCHEMBL6794515 | 0.79 | F7 (0.44) | F7F3GAAMAPT | |
| SCHEMBL8360872 | 0.77 | F7 (0.43) | F7F3ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028729-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |