Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 12/20 | 0.43 |
| ▸ | F3 | P13726 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | GUSB | P08236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8360311 | 0.89 | F7 (0.40) | F7F3ALDH1A1GAAMAPT | |
| SCHEMBL8363188 | 0.86 | F7 (0.55) | F7F3SYK | |
| SCHEMBL6791732 | 0.86 | F7 (0.48) | F7F3ALDH1A1SYK | |
| SCHEMBL6791726 | 0.86 | F7 (0.48) | F7F3ALDH1A1SYK | |
| SCHEMBL6794526 | 0.85 | F7 (0.44) | F7F3GAAMAPTLMNA | |
| SCHEMBL6794515 | 0.85 | F7 (0.44) | F7F3GAAMAPTLMNA | |
| SCHEMBL8360874 | 0.85 | F7 (0.42) | F7F3GAAMAPTKDM4E | |
| SCHEMBL6797477 | 0.82 | F7 (0.43) | F7F3ALDH1A1GAASYK | |
| SCHEMBL6797466 | 0.82 | F7 (0.43) | F7F3ALDH1A1GAASYK | |
| SCHEMBL6791505 | 0.82 | F7 (0.52) | F7F3MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028729-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |