Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 15/20 | 0.60 |
| ▸ | F3 | P13726 | 4/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8363570 | 0.93 | F7 (0.64) | F7F3PRSS1F2HDAC6 | |
| SCHEMBL8363200 | 0.93 | F7 (0.70) | F7F3PRSS1F2HDAC6 | |
| SCHEMBL8363355 | 0.91 | F7 (0.62) | F7F3PRSS1F2HDAC6 | |
| SCHEMBL8360129 | 0.88 | F7 (0.59) | F7F3PRSS1F2HDAC6 | |
| SCHEMBL8360799 | 0.87 | F7 (0.64) | F7F3PRSS1F2 | |
| SCHEMBL8360103 | 0.87 | F7 (0.60) | F7F3PRSS1F2HDAC6 | |
| SCHEMBL6792785 | 0.87 | F7 (0.60) | F7F3PRSS1F2HDAC6 | |
| SCHEMBL8363544 | 0.86 | F7 (0.62) | F7F3PRSS1F2 | |
| SCHEMBL6799050 | 0.85 | F7 (0.59) | F7F3PRSS1F2HDAC6 | |
| SCHEMBL8360839 | 0.84 | F7 (0.46) | F7F3PRSS1F2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028729-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |