Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 13/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.43 |
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | F3 | P13726 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8362509 | 0.91 | F7 (0.54) | F7HDAC6F2F3HDAC4 | |
| SCHEMBL6791169 | 0.84 | F7 (0.64) | F7F2F3PRSS1 | |
| SCHEMBL8360327 | 0.84 | F7 (0.60) | F7HDAC6F2F3HDAC4 | |
| SCHEMBL8360894 | 0.84 | F7 (0.51) | F7F2F3PRSS1PRSS2 | |
| SCHEMBL8363693 | 0.83 | F7 (0.53) | F7F2F3PRSS1PRSS2 | |
| SCHEMBL8360338 | 0.82 | F7 (0.56) | F7F2F3PRSS1PRSS2 | |
| SCHEMBL8363570 | 0.81 | F7 (0.64) | F7HDAC6F2F3HDAC4 | |
| SCHEMBL8363200 | 0.81 | F7 (0.70) | F7HDAC6F2F3HDAC4 | |
| SCHEMBL8363355 | 0.79 | F7 (0.62) | F7HDAC6F2F3HDAC4 | |
| SCHEMBL6790244 | 0.78 | F7 (0.50) | F7F2F3PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028729-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |