Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 10/20 | 0.41 |
| ▸ | PLAU | P00749 | 10/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8360974 | 0.84 | C1S (0.36) | C1SPLAU | |
| SCHEMBL8360980 | 0.83 | PLAU (0.51) | C1SPLAUPLGPLATPRSS1 | |
| SCHEMBL8360414 | 0.79 | C1S (0.48) | C1SPLAUPLGPLATPRSS1 | |
| SCHEMBL6209983 | 0.72 | C1S (0.67) | C1S | |
| Hydrochloric Acid SCHEMBL5842010 | 0.71 | C1S (0.66) | C1S | |
| SCHEMBL8363738 | 0.70 | PLAU (0.49) | C1SPLAU | |
| SCHEMBL8363266 | 0.70 | PLAU (0.54) | C1SPLAUPLGPLATPRSS1 | |
| SCHEMBL8363639 | 0.68 | C1S (0.56) | C1SPLAUPLGPLATPRSS1 | |
| Trifluoroacetic Acid SCHEMBL5845415 | 0.66 | C1S (0.58) | C1S | |
| SCHEMBL8363254 | 0.65 | PLAU (0.57) | C1SPLAUPLGPLATPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099805-A1 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-12-04 | — | — | WO | disclosed |