SCHEMBL8360974

SCHEMBL8360974

C=CCOc1cc(Br)cc([S+]([O-])c2cc(C(=N)N)sc2SC)c1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
C1S P09871 17/20 0.36
PLAU P00749 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8360413 0.84 C1S (0.41) C1SPLAU
Hydrochloric Acid SCHEMBL5842001 0.75 C1S (0.58) C1S
SCHEMBL8363738 0.71 PLAU (0.49) C1SPLAU
Trifluoroacetic Acid SCHEMBL5841047 0.70 C1S (0.52) C1S
SCHEMBL8360980 0.69 PLAU (0.51) C1SPLAU
SCHEMBL8360414 0.65 C1S (0.48) C1SPLAU
SCHEMBL8363266 0.65 PLAU (0.54) C1SPLAU
SCHEMBL5841296 0.64 C1S (0.65) C1S
SCHEMBL8363639 0.63 C1S (0.56) C1SPLAU
SCHEMBL5841360 0.63 C1S (0.43) C1S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003099805-A1 NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2003-12-04 WO disclosed