Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.67 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.67 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8357212 | 0.85 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5703617 | 0.84 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7863442 | 0.83 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7863418 | 0.83 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7426106 | 0.83 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6545912 | 0.83 | PDE4B (0.86) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6545916 | 0.83 | PDE4B (0.86) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5495203 | 0.80 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7321654 | 0.80 | PDE4A (0.82) | PDE4APDE4BPDE4CPDE4D | |
| Bicarbonate SCHEMBL4603657 | 0.79 | PDE4A (0.80) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016596-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS PDE-IV INHIBITORS FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS | GLENMARK PHARMACEUTICALS LIMITED (US) | 2004-02-26 | — | — | WO | disclosed |