Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8361951 | 0.80 | DPP4 (0.65) | DPP4DPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL4911278 | 0.79 | DPP4 (0.64) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL11932504 | 0.70 | CYP2D6 (0.65) | KCNH2NPSR1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11887346 | 0.69 | CYP2D6 (0.79) | KCNH2NPSR1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2859526 | 0.69 | DPP4 (0.50) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2859518 | 0.69 | DPP4 (0.50) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL28293514 | 0.69 | CYP2D6 (0.51) | KCNH2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7300452 | 0.67 | DPP4 (0.62) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL7291392 | 0.67 | DPP4 (0.62) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL14523897 | 0.67 | DPP4 (1.00) | DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | FERRING B.V. | 2008-10-16 | — | — | US | disclosed |
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | FERRING B.V. | 2008-10-16 | — | — | US | disclosed |
| US-7335677-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING B.V. (NL) | 2008-02-26 | — | — | US | disclosed |
| US-7335677-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING B.V. (NL) | 2008-02-26 | — | — | US | disclosed |
| WO-2003035057-A1 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | FERRING B.V. (NL) | 2003-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | PREP, PEPD, DPP4 | DPP4 3/4885DPP7 7/4885DPP8 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.