Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GPX4 | P36969 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3574211 | 0.78 | CYP11B1 (0.66) | MEN1KMT2ACYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL3574374 | 0.78 | CYP11B1 (0.65) | MEN1KMT2ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL5769986 | 0.66 | CYP11B1 (0.72) | CYP11B1CYP11B2ALDH1A1CYP3A4 | |
| SCHEMBL1065113 | 0.63 | HDAC1 (0.61) | CYP19A1 | |
| SCHEMBL14679534 | 0.60 | NISCH (0.43) | MEN1KMT2ASMN1; SMN2ALDH1A1CA1 | |
| SCHEMBL6158387 | 0.60 | TSHR (0.67) | SMN1; SMN2ALDH1A1MAPTCA1CA2 | |
| SCHEMBL1928912 | 0.60 | TSHR (0.67) | SMN1; SMN2ALDH1A1MAPTTP53CA1 | |
| SCHEMBL31611736 | 0.60 | TSHR (0.60) | MEN1KMT2ASMN1; SMN2ALDH1A1HSP90AA1 | |
| SCHEMBL13984796 | 0.60 | TSHR (0.60) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| Methyl Benzoate SCHEMBL28249321 | 0.59 | TSHR (0.95) | MEN1KMT2ASMN1; SMN2ALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014914-A1 | ORGANIC COMPOUNDS AS AGENTS FOR THE TREATMENT OF ALDOSTERONE MEDIATED CONDITIONS | NOVARTIS AG (CH) | 2004-02-19 | — | — | WO | disclosed |