SCHEMBL8360966

SCHEMBL8360966

OCCN(CCO)Nc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.37
RAB9A P51151 1/20 0.37
KCNH3 Q9ULD8 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
RECQL P46063 1/20 0.36
MCL1 Q07820 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 5/20 0.36
TDP1 Q9NUW8 3/20 0.36
HSD17B10 Q99714 3/20 0.36
CTSD P07339 1/20 0.36
GAA P10253 3/20 0.36
LMNA P02545 2/20 0.36
LIMK2 P53671 1/20 0.35
TSHR P16473 2/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
PTGS1 P23219 1/20 0.35
SLC6A2 P23975 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL14831105 0.89 LIMK2 (0.39) SMN1; SMN2RAB9AL3MBTL1KDM4EALDH1A1
SCHEMBL7716881 0.88 KDM4E (0.47) IDO1RAB9AL3MBTL1KDM4EALDH1A1
Sulfuric Acid SCHEMBL3630424 0.80 L3MBTL1 (0.45) SMN1; SMN2RAB9AL3MBTL1RECQLKDM4E
SCHEMBL2314438 0.78 MAPT (0.39) SMN1; SMN2RAB9AL3MBTL1KDM4EALDH1A1
SCHEMBL5827178 0.78 KDM4E (0.50) RAB9AL3MBTL1KDM4EALDH1A1TDP1
SCHEMBL2896837 0.77 KDM4E (0.40) L3MBTL1KDM4EALDH1A1TDP1HSD17B10
SCHEMBL5309294 0.77 HTT (0.36) IDO1SMN1; SMN2RAB9AL3MBTL1RECQL
SCHEMBL6365866 0.77 MAPT (0.48) L3MBTL1KDM4EALDH1A1HSD17B10GAA
SCHEMBL6366972 0.77 MAPT (0.46) IDO1SMN1; SMN2RAB9AALDH1A1TDP1
Hydrochloric Acid SCHEMBL8507986 0.76 HTT (0.35) IDO1SMN1; SMN2RAB9AL3MBTL1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722713-B1 Composition for oxidative dyeing of keratin fibers and process of dyeing using that composition OREAL (FR) 1997-08-06 EP claimed
US-11203708-B2 Gas generating compositions SAUDI ARABIAN OIL COMPANY (SA) 2021-12-21 US disclosed
US-20210047552-A1 GAS GENERATING COMPOSITIONS ARAMCO SERVICES COMPANY 2021-02-18 US disclosed
US-10590326-B1 Storable gas generating compositions SAUDI ARABIAN OIL COMPANY (SA) 2020-03-17 US disclosed
EP-2760418-A1 FOAM DYE COMPOSITION COMPRISING A POLYCONDENSATE OF ETHYLENE OXIDE AND PROPYLENE OXIDE L'Oréal (FR) 2014-08-06 EP disclosed
EP-2760416-A1 FOAM DYE COMPOSITION COMPRISING AT LEAST ONE PARTICULAR OXYETHYLENATED NONIONIC SURFACTANT L'Oréal (FR) 2014-08-06 EP disclosed
EP-2760422-A1 FOAM DYE COMPOSITION COMPRISING AT LEAST ONE LIQUID FATTY ALCOHOL AND A PARTICULAR CATIONIC POLYMER L'Oréal (FR) 2014-08-06 EP disclosed
WO-2013045630-A1 FOAM DYE COMPOSITION COMPRISING AT LEAST ONE LIQUID FATTY ALCOHOL AND A PARTICULAR CATIONIC POLYMER L'OREAL (FR) 2013-04-04 WO disclosed
WO-2013045627-A1 FOAM DYE COMPOSITION COMPRISING AT LEAST TWO DIOL COMPOUNDS EACH COMPRISING AT LEAST 4 CARBON ATOMS L'OREAL (FR) 2013-04-04 WO disclosed
WO-2013045626-A1 FOAM DYE COMPOSITION COMPRISING A POLYCONDENSATE OF ETHYLENE OXIDE AND PROPYLENE OXIDE L'OREAL (FR) 2013-04-04 WO disclosed
WO-2013045628-A1 FOAM DYE COMPOSITION COMPRISING AT LEAST ONE PARTICULAR OXYETHYLENATED NONIONIC SURFACTANT L'OREAL (FR) 2013-04-04 WO disclosed
US-5968206-A HAIR DYES L'OREAL (FR) 1999-10-19 US disclosed
US-5344464-A Hair dyes with para-phenylenediamine and N,N*-diphenyl-alkylenediamine dye precursors for keratin fibers L'OREAL (FR) 1994-09-06 US disclosed
EP-0366542-B1 5-SUBSTITUTED ORTHO-AMINOPHENOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE OXIDATION DYEING OF KERATINIC FIBRES L'OREAL (FR) 1993-07-14 EP disclosed
US-5186717-A Colorfastness, hair dyes L'OREAL (FR) 1993-02-16 US disclosed
EP-0366542-A1 5-Substituted ortho-aminophenols, process for their preparation and their use in the oxidation dyeing of keratinic fibres L'OREAL (FR) 1990-05-02 EP disclosed
US-4419101-A Chlorine-substituted nitro-para-phenylenediamines, a process for their preparation and their use in dyeing keratin fibres L'OREAL (FR) 1983-12-06 US disclosed