⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007470 | 0.78 | — | — | |
| SCHEMBL4898562 | 0.73 | — | — | |
| SCHEMBL8007469 | 0.73 | — | — | |
| SCHEMBL6596606 | 0.73 | — | — | |
| SCHEMBL13718802 | 0.71 | — | — | |
| SCHEMBL6131428 | 0.71 | — | — | |
| SCHEMBL835304 | 0.69 | — | — | |
| SCHEMBL19988825 | 0.69 | — | — | |
| SCHEMBL8404883 | 0.69 | — | — | |
| SCHEMBL835616 | 0.67 | MAPT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10323033-B2 | Imidazo[1,2-A]pyridine-3-carboxylate derivative and preparation method thereof | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2019-06-18 | — | — | US | disclosed |
| US-20180354948-A1 | IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLATE DERIVATIVE AND PREPARATION METHOD THEREOF | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2018-12-13 | — | — | US | disclosed |
| US-20170065575-A1 | NAMPT INHIBITORS | ABBVIE INC (US) | 2017-03-09 | — | — | US | disclosed |
| US-20150141398-A1 | NAMPT INHIBITORS | ABBVIE INC. | 2015-05-21 | — | — | US | disclosed |
| EP-2852585-A1 | NAMPT INHIBITORS | AbbVie Inc. (US) | 2015-04-01 | — | — | EP | disclosed |
| EP-2847181-A1 | PYRIDAZINE AND PYRIDINE DERIVATIVES AS NAMPT INHIBITORS | AbbVie Inc. (US) | 2015-03-18 | — | — | EP | disclosed |
| WO-2013170113-A1 | NAMPT INHIBITORS | ABBVIE INC. (US) | 2013-11-14 | — | — | WO | disclosed |
| WO-2013170115-A1 | PYRIDAZINE AND PYRIDINE DERIVATIVES AS NAMPT INHIBITORS | ABBVIE INC. (US) | 2013-11-14 | — | — | WO | disclosed |
| US-8497397-B2 | Substituted acrylamide derivative and pharmaceutical composition comprising the same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-07-30 | — | — | US | disclosed |
| EP-1880720-B1 | SUBSTITUTED ACRYLAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAIICHI SANKYO CO LTD (JP) | 2013-02-13 | — | — | EP | disclosed |
| EP-0047491-B1 | NEW CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-06-24 | — | — | EP | disclosed |
| EP-0184227-A1 | 2-Oxymino 2-aminothiazolyl acetic acid derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-06-11 | — | — | EP | disclosed |
| US-4533738-A | THIAZOLE INTERMEDIATES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-08-06 | — | — | US | disclosed |
| US-4416879-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-22 | — | — | US | disclosed |
| EP-0047491-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-03-17 | — | — | EP | disclosed |
| US-4108631-A | HERBICIDES, INSECTICIDES | ELI LILLY AND COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-RE29508-E | HERBICIDES AND INSECTICIDES | ELI LILLY AND COMPANY (US) | 1978-01-03 | — | — | US | disclosed |
| US-4011341-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1977-03-08 | — | — | US | disclosed |
| US-3989840-A | Control of animal parasites with ring-substituted N-(2,2-difluoroalkanoyl)-O-phenylenediamines | ELI LILLY AND COMPANY (US) | 1976-11-02 | — | — | US | disclosed |
| US-3962263-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |