Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28433233 | 1.00 | HDAC3 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4834310 | 0.98 | HDAC3 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8584248 | 0.95 | HDAC3 (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27533156 | 0.93 | ALDH1A1 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9468429 | 0.89 | ALDH1A1 (0.50) | MAPTMAPK1SMN1; SMN2LMNATSHR | |
| SCHEMBL5523432 | 0.87 | ALDH1A1 (0.52) | HDAC8MAPTMAPK1SMN1; SMN2TSHR | |
| Succinic Acid SCHEMBL22217135 | 0.87 | NR4A2 (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL125859 | 0.87 | NR4A2 (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Maleic Acid SCHEMBL28187597 | 0.86 | ALDH1A1 (0.42) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL30364316 | 0.84 | ALDH1A1 (0.60) | HDAC6MAPTMAPK1SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102336946-A | Rail transit rubber cable sheath material, its preparation method and application | ZHEJIANG WANMA CABLE CO LTD | 2012-02-01 | — | — | CN | disclosed |
| US-5932030-A | NONTOXIC MIXTURE CONTAINING ROSIN AND N-SUBSTITUTED OR UNSUBSTITUTED 2-PYRROLIDONE | SONY CORPORATION (JP) | 1999-08-03 | — | — | US | disclosed |
| US-5116412-A | Metal salt and polyol | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-26 | — | — | US | disclosed |
| EP-0409433-A1 | Internal mould release compositions | ATLAS EUROPOL SpA (IT) | 1991-01-23 | — | — | EP | disclosed |
| US-4983659-A | POLYUREA ELASTOMERS | ICI AMERICAS INC. (US) | 1991-01-08 | — | — | US | disclosed |
| US-4301186-A | FOR IN SITU DECOMPOSITION BY RADIATION TO PRODUCE AMINES FOR HARDENING A POLYURETHANE OR EPOXY RESIN MONOMERS SOLUTION | BAYER AKTIENGESELLSCHAFT (DE) | 1981-11-17 | — | — | US | disclosed |