Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | CTSG | P08311 | 2/20 | 0.35 |
| ▸ | PLAU | P00749 | 3/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.33 |
| ▸ | ITGAV | P06756 | 6/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 4/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.32 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8227193 | 0.97 | CTSL (0.58) | CTSLDRD1PTGS1PDE4ACTSG | |
| SCHEMBL8424783 | 0.97 | CTSL (0.58) | CTSLDRD1PTGS1PDE4ACTSG | |
| SCHEMBL8242592 | 0.97 | CTSL (0.58) | CTSLDRD1PTGS1PDE4ACTSG | |
| SCHEMBL14215178 | 0.95 | CTSL (0.57) | CTSLDRD1PTGS1PDE4ACTSG | |
| SCHEMBL8244573 | 0.91 | CTSL (0.64) | CTSLDRD1PTGS1PDE4ACTSG | |
| SCHEMBL8227371 | 0.91 | CTSL (0.64) | CTSLDRD1PTGS1PDE4ACTSG | |
| SCHEMBL8242455 | 0.89 | CTSL (0.60) | CTSLDRD1PTGS1PDE4ACTSG | |
| SCHEMBL8244946 | 0.88 | CTSL (0.59) | CTSLDRD1PTGS1PDE4ACTSG | |
| SCHEMBL8242626 | 0.88 | CTSL (0.53) | CTSLDRD1PTGS1PDE4ACTSG | |
| SCHEMBL8242481 | 0.88 | CTSL (0.53) | CTSLDRD1PTGS1PDE4ACTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003014147-A1 | NOVEL DEPSIPEPTIDES AND PROCESS FOR PREPARING SAME | CUBIST PHARMACEUTICALS, INC. (US) | 2003-02-20 | — | — | WO | disclosed |