Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 10/20 | 0.50 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793924 | 0.88 | F7 (0.54) | F7SOS1GRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL6795206 | 0.87 | F7 (0.53) | F7SOS1GRIN1GRIN2B | |
| SCHEMBL6796881 | 0.78 | F7 (0.49) | F7 | |
| SCHEMBL8360265 | 0.77 | F7 (0.65) | F7 | |
| SCHEMBL8360173 | 0.77 | F7 (0.71) | F7 | |
| SCHEMBL8363577 | 0.76 | F7 (0.73) | F7 | |
| SCHEMBL8360246 | 0.76 | F7 (0.73) | F7 | |
| SCHEMBL8360919 | 0.76 | F7 (0.68) | F7 | |
| SCHEMBL6795150 | 0.76 | F7 (0.55) | F7 | |
| SCHEMBL8361853 | 0.76 | F7 (0.69) | F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028729-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |