Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.68 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.68 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | NAMPT | P43490 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1339196 | 0.98 | PTPN1 (0.71) | PTPN1HPGDENPP3ENPP1ENPP2 | |
| SCHEMBL7863859 | 0.95 | PTPN1 (0.66) | PTPN1HPGDENPP3ENPP1ENPP2 | |
| SCHEMBL7865123 | 0.91 | NAMPT (0.72) | PTPN1ENPP3ENPP1ENPP2NPSR1 | |
| SCHEMBL28656982 | 0.91 | PTPN1 (0.89) | PTPN1HPGDENPP3ENPP1ENPP2 | |
| SCHEMBL125695 | 0.91 | PTPN1 (0.89) | PTPN1HPGDENPP3ENPP1ENPP2 | |
| Hydrochloric Acid SCHEMBL435505 | 0.89 | NAMPT (0.70) | PTPN1ENPP3ENPP1ENPP2NPSR1 | |
| SCHEMBL13105759 | 0.86 | PTPN1 (0.74) | PTPN1HPGDENPP3ENPP1ENPP2 | |
| SCHEMBL29057710 | 0.84 | PTPN1 (0.77) | PTPN1HPGDENPP3ENPP1ENPP2 | |
| SCHEMBL9851155 | 0.84 | PTPN1 (0.77) | PTPN1HPGDENPP3ENPP1ENPP2 | |
| SCHEMBL13144615 | 0.83 | ALDH1A1 (0.58) | ENPP3ENPP1ENPP2NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050825-A1 | COMPOUNDS AS MLKL INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2024-03-14 | — | — | WO | disclosed |
| EP-3049387-B1 | THERMOPLASTIC POLYMER COMPOSITION | MILLIKEN & CO (US) | 2020-11-11 | — | — | EP | disclosed |
| EP-2373634-B1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARM CO LTD (JP) | 2015-11-11 | — | — | EP | disclosed |
| US-7220532-B2 | Chemical amplification type resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-22 | — | — | US | disclosed |
| US-7220532-B2 | Chemical amplification type resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-22 | — | — | US | disclosed |
| WO-2003007954-A2 | SULFONYL ARYL HYDROXAMATES AND THEIR USE AS MATRIX METALLOPROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2003-01-30 | — | — | WO | disclosed |