SCHEMBL8364136

SCHEMBL8364136

CNC(=O)c1ccc(/C=C/C(=O)NCC(=O)N(C)c2ccc(C)c(COc3cccc4c(C(=O)NC)cc(C)nc34)c2C)cc1

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 19/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8364137 1.00 BDKRB2 (0.83) BDKRB2
SCHEMBL8365919 0.96 BDKRB2 (0.83) BDKRB2
SCHEMBL8365921 0.96 BDKRB2 (0.83) BDKRB2
SCHEMBL8361800 0.95 BDKRB2 (0.79) BDKRB2
SCHEMBL8361804 0.95 BDKRB2 (0.79) BDKRB2
SCHEMBL8366140 0.94 BDKRB2 (0.85) BDKRB2
SCHEMBL8366136 0.94 BDKRB2 (0.85) BDKRB2
SCHEMBL8366172 0.93 BDKRB2 (0.82) BDKRB2
SCHEMBL8366171 0.93 BDKRB2 (0.82) BDKRB2
SCHEMBL8364154 0.93 BDKRB2 (0.84) BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5994368-A ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANALGESICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-11-30 US disclosed