Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676454 | 0.95 | ITGB3 (0.60) | ITGB3ITGA2BALDH1A1KDM4EMAPT | |
| SCHEMBL6676450 | 0.95 | ITGB3 (0.60) | ITGB3ITGA2BALDH1A1KDM4EMAPT | |
| SCHEMBL2784278 | 0.85 | ITGB3 (0.47) | ITGB3ITGA2BALDH1A1KDM4EMAPT | |
| SCHEMBL2786680 | 0.85 | ITGB3 (0.47) | ITGB3ITGA2BALDH1A1KDM4EMAPT | |
| SCHEMBL2784223 | 0.85 | ITGB3 (0.47) | ITGB3ITGA2BALDH1A1KDM4EMAPT | |
| SCHEMBL6423850 | 0.81 | PPARD (0.47) | ITGB3ITGA2BALDH1A1ITGAV | |
| SCHEMBL6419319 | 0.81 | PPARD (0.47) | ITGB3ITGA2BALDH1A1ITGAV | |
| SCHEMBL6419323 | 0.81 | PPARD (0.47) | ITGB3ITGA2BALDH1A1ITGAV | |
| SCHEMBL6419594 | 0.77 | ITGB3 (0.46) | ITGB3ITGA2BITGAV | |
| SCHEMBL6679726 | 0.77 | ITGB3 (0.51) | ITGB3ITGA2BALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977101-A | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |