Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PPIA | P62937 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364295 | 1.00 | BRD4 (0.64) | BRD4L3MBTL1TDP1PPIAPOLB | |
| SCHEMBL11723616 | 0.82 | GAA (0.45) | BRD4L3MBTL1TDP1POLBALDH1A1 | |
| SCHEMBL11723587 | 0.82 | GAA (0.45) | BRD4L3MBTL1TDP1POLBALDH1A1 | |
| SCHEMBL5033321 | 0.81 | IDO1 (0.48) | BRD4PPIAALDH1A1KMT2ANPC1 | |
| SCHEMBL5033317 | 0.81 | IDO1 (0.48) | BRD4PPIAALDH1A1KMT2ANPC1 | |
| SCHEMBL3645648 | 0.81 | ALDH1A1 (0.66) | ALDH1A1NPC1RAB9A | |
| SCHEMBL3645649 | 0.81 | ALDH1A1 (0.66) | ALDH1A1NPC1RAB9A | |
| SCHEMBL5040549 | 0.80 | MEN1 (0.55) | ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL5040554 | 0.80 | MEN1 (0.55) | ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL5516774 | 0.80 | ALDH1A1 (0.45) | BRD4PPIAALDH1A1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994368-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0807105-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996013485-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-09 | — | — | WO | disclosed |