SCHEMBL8364374

SCHEMBL8364374

COC(=O)C1CCC(C(=O)NCCCCCCNC(=O)C2CCC(C(=O)OC)CC2)CC1

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.57
GNAI3 P08754 3/20 0.53
GNAO1 P09471 3/20 0.53
GNAI1 P63096 3/20 0.53
CYP3A4 P08684 1/20 0.47
KMT2A Q03164 1/20 0.44
PRCP P42785 1/20 0.44
TSHR P16473 1/20 0.43
CNR1 P21554 2/20 0.43
CNR2 P34972 2/20 0.43
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
GAA P10253 1/20 0.41
NAMPT P43490 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9511929 0.81 NAAA (0.83) NAAAGNAI3GNAO1GNAI1PRCP
SCHEMBL1678750 0.81 NAAA (0.83) NAAAGNAI3GNAO1GNAI1PRCP
SCHEMBL3578682 0.81 GAA (0.47) NAAAGNAI3GNAO1GNAI1CYP3A4
SCHEMBL3578679 0.81 GAA (0.47) NAAAGNAI3GNAO1GNAI1CYP3A4
SCHEMBL377246 0.79 NAAA (0.79) NAAAGNAI3GNAO1GNAI1PRCP
SCHEMBL16864015 0.78 EPHX2 (0.50) NAAAGNAI3GNAO1GNAI1CYP3A4
SCHEMBL2576766 0.78 KMT2A (0.44) KMT2AKDM4EALDH1A1GAA
SCHEMBL2576767 0.78 KMT2A (0.44) KMT2AKDM4EALDH1A1GAA
SCHEMBL2582971 0.78 KMT2A (0.53) KMT2AALDH1A1GAA
SCHEMBL2582969 0.78 KMT2A (0.53) KMT2AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5939519-A CRYSTALLINITY OF POLY(1,4-CYCLOHEXANEDIMETHYL 1,4-CYCLOHEXANEDICARBOXYLATE) IS ENHANCED BY THE INCORPORATION OF AMIDE UNITS, PREFERABLY DERIVED FROM SUCH COMPOUNDS AS 1,6-BIS(4-CARBOMETHOXYCYCLOHEXYLCARBOXAMIDO)HEXANE GENERAL ELECTRIC CO. (US) 1999-08-17 US disclosed
US-5939519-A CRYSTALLINITY OF POLY(1,4-CYCLOHEXANEDIMETHYL 1,4-CYCLOHEXANEDICARBOXYLATE) IS ENHANCED BY THE INCORPORATION OF AMIDE UNITS, PREFERABLY DERIVED FROM SUCH COMPOUNDS AS 1,6-BIS(4-CARBOMETHOXYCYCLOHEXYLCARBOXAMIDO)HEXANE GENERAL ELECTRIC CO. (US) 1999-08-17 US disclosed