Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.47 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364399 | 0.98 | ALDH1A1 (0.53) | ALDH1A1TSHRCNR1CNR2MEN1 | |
| SCHEMBL8364380 | 0.97 | ALDH1A1 (0.54) | ALDH1A1TSHRCNR1CNR2MEN1 | |
| SCHEMBL8364214 | 0.96 | CNR1 (0.54) | ALDH1A1TSHRCNR1CNR2MEN1 | |
| SCHEMBL8364321 | 0.91 | KDM4E (0.45) | ALDH1A1TSHRMEN1LMNAMAPT | |
| SCHEMBL8363837 | 0.91 | CNR1 (0.52) | ALDH1A1TSHRCNR1CNR2MEN1 | |
| SCHEMBL8363854 | 0.89 | CNR1 (0.53) | ALDH1A1TSHRCNR1CNR2MEN1 | |
| SCHEMBL8363847 | 0.89 | TSHR (0.50) | ALDH1A1TSHRCNR1CNR2MEN1 | |
| SCHEMBL8364397 | 0.87 | CNR1 (0.51) | ALDH1A1TSHRCNR1CNR2MEN1 | |
| SCHEMBL8363838 | 0.86 | CNR1 (0.50) | ALDH1A1TSHRCNR1CNR2MEN1 | |
| SCHEMBL8363853 | 0.86 | TSHR (0.50) | ALDH1A1TSHRCNR1CNR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003013527-A1 | SULFONAMIDE DERIVATIVES AS GAMMA SECRETASE INHIBITORS | SCHERING CORPORATION (US) | 2003-02-20 | — | — | WO | disclosed |