Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364577 | 1.00 | ATM (0.53) | ATMHCAR2MAPTRAB9ANPSR1 | |
| Diethyl Maleate SCHEMBL8366376 | 0.86 | HCAR2 (0.42) | ATMHCAR2MAPTNPSR1ALDH1A1 | |
| Diethyl Maleate SCHEMBL8366375 | 0.86 | HCAR2 (0.42) | ATMHCAR2MAPTNPSR1ALDH1A1 | |
| SCHEMBL4605785 | 0.82 | ATM (0.61) | ATMHCAR2MAPTRAB9ANPSR1 | |
| Dimethyl Fumarate SCHEMBL8364739 | 0.82 | HCAR2 (0.42) | HCAR2 | |
| Dimethyl Maleate SCHEMBL8364738 | 0.82 | HCAR2 (0.42) | HCAR2 | |
| SCHEMBL4605788 | 0.77 | ATM (0.57) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL108806 | 0.75 | ATM (0.55) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL107869 | 0.75 | ATM (0.55) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL107870 | 0.75 | ATM (0.55) | ATMHCAR2MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001946-A | Curable silane-encapped compositions having improved performances | WITCO CORPORATION (US) | 1999-12-14 | — | — | US | disclosed |