Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 8/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethyl Maleate SCHEMBL8366375 | 1.00 | HCAR2 (0.42) | HCAR2MAOBCA12CA1CA2 | |
| Dimethyl Maleate SCHEMBL8364738 | 0.86 | HCAR2 (0.42) | HCAR2CA12CA1CA2CA7 | |
| Dimethyl Fumarate SCHEMBL8364739 | 0.86 | HCAR2 (0.42) | HCAR2CA12CA1CA2CA7 | |
| SCHEMBL8364574 | 0.86 | ATM (0.53) | HCAR2MAPTLMNAATMALDH1A1 | |
| SCHEMBL8364577 | 0.86 | ATM (0.53) | HCAR2MAPTLMNAATMALDH1A1 | |
| SCHEMBL57138 | 0.79 | CYP2D6 (0.41) | — | |
| SCHEMBL4653307 | 0.69 | CYP2D6 (0.32) | — | |
| Diethyl Maleate SCHEMBL43033 | 0.69 | HCAR2 (0.80) | HCAR2CA12CA1CA2CA7 | |
| Diethyl Maleate SCHEMBL60423 | 0.69 | HCAR2 (0.80) | HCAR2CA12CA1CA2CA7 | |
| Diethyl Maleate SCHEMBL2015895 | 0.69 | HCAR2 (0.80) | HCAR2CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001946-A | Curable silane-encapped compositions having improved performances | WITCO CORPORATION (US) | 1999-12-14 | — | — | US | disclosed |