Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7739985 | 0.75 | POLB (0.38) | POLBFABP5FABP3ALDH1A1MAPT | |
| SCHEMBL2354458 | 0.73 | S100A4 (0.41) | CYP19A1EDNRBEDNRAALDH1A1MAPT | |
| SCHEMBL12719040 | 0.66 | KDM1A (0.44) | KMT2A | |
| SCHEMBL1970316 | 0.63 | CHRNB4 (0.36) | MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL7508993 | 0.61 | MAOB (0.58) | POLBCYP19A1CYP11B2MEN1ALDH1A1 | |
| SCHEMBL11677796 | 0.61 | HTR2A (0.46) | — | |
| SCHEMBL30667179 | 0.60 | CYP19A1 (0.50) | CYP19A1CYP11B2ALDH1A1MAPTHPGD | |
| SCHEMBL9755397 | 0.60 | CDC25A (0.38) | POLBALDH1A1MAPTTDP1HPGD | |
| SCHEMBL7959973 | 0.60 | CYP19A1 (0.50) | CYP19A1CYP11B2ALDH1A1MAPTHPGD | |
| SCHEMBL1057092 | 0.59 | CYP1A2 (0.31) | MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699909-B1 | MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS; CENTRAL NERVOUS SYSTEM DISORDERS | PRESCIENT NEUROPHARMA INC. (CA) | 2004-03-02 | — | — | US | disclosed |