Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 17/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8367798 | 0.89 | BDKRB2 (0.51) | BDKRB2 | |
| SCHEMBL8364329 | 0.84 | BDKRB2 (0.44) | BDKRB2CYP3A4 | |
| SCHEMBL8367618 | 0.83 | BDKRB2 (0.43) | BDKRB2CYP3A4GAAPOLB | |
| SCHEMBL8810603 | 0.78 | BDKRB2 (0.39) | BDKRB2CYP3A4RXFP1 | |
| SCHEMBL7749582 | 0.78 | BDKRB2 (0.51) | BDKRB2 | |
| SCHEMBL6643730 | 0.77 | BDKRB2 (0.56) | BDKRB2 | |
| SCHEMBL6643996 | 0.77 | BDKRB2 (0.58) | BDKRB2 | |
| SCHEMBL6642693 | 0.76 | BDKRB2 (0.58) | BDKRB2 | |
| SCHEMBL8367347 | 0.76 | BDKRB2 (0.57) | BDKRB2 | |
| SCHEMBL6645090 | 0.75 | POLB (0.43) | GAATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994368-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0807105-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996013485-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-09 | — | — | WO | disclosed |