Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364930 | 1.00 | MAPT (0.73) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL8368077 | 0.84 | ALDH1A1 (1.00) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL8368078 | 0.84 | ALDH1A1 (1.00) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL14342663 | 0.84 | KDM4E (0.74) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL8366640 | 0.83 | ALDH1A1 (0.73) | MAPTKDM4EALDH1A1CA1CA2 | |
| SCHEMBL8369820 | 0.83 | ALDH1A1 (0.73) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL8369822 | 0.83 | ALDH1A1 (0.73) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL8366639 | 0.83 | ALDH1A1 (0.73) | MAPTKDM4EALDH1A1CA1CA2 | |
| SCHEMBL4285935 | 0.82 | ALDH1A1 (0.67) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL8364647 | 0.82 | ALDH1A1 (0.67) | MAPTKDM4EALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |