Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.43 |
| ▸ | MC5R | P33032 | 2/20 | 0.43 |
| ▸ | MC3R | P41968 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.39 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.39 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.38 |
| ▸ | CHRNG | P07510 | 2/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850361 | 1.00 | MC4R (0.43) | MC4RMC5RMC3RF2OPRD1 | |
| SCHEMBL7860791 | 0.93 | MC4R (0.48) | MC4RMC5RMC3RF2LTA4H | |
| SCHEMBL7857110 | 0.86 | LTA4H (0.45) | MC4RMC5RMC3RF2LTA4H | |
| SCHEMBL7857976 | 0.85 | LARS1 (0.46) | F2KDM4EMEN1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7857842 | 0.82 | LARS1 (0.42) | F2LTA4HCYP1A2MAPTSMN1; SMN2 | |
| SCHEMBL8362644 | 0.81 | EPHX1 (0.39) | MC4RMC5RMC3RF2KDM4E | |
| SCHEMBL7859247 | 0.81 | EPHX1 (0.39) | MC4RMC5RMC3RF2KDM4E | |
| SCHEMBL4610411 | 0.80 | BACE1 (0.57) | OPRD1BACE1KDM4EMEN1KMT2A | |
| SCHEMBL29641523 | 0.78 | SLC7A5 (0.52) | MC4RMC5RMC3RLNPEP | |
| SCHEMBL29909939 | 0.78 | SLC7A5 (0.52) | MC4RMC5RMC3RLNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |