Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 8/20 | 0.50 |
| ▸ | NPY4R | P50391 | 8/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.50 |
| ▸ | NPY1R | P25929 | 7/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.48 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | RAMP3 | O60896 | 2/20 | 0.45 |
| ▸ | CALCR | P30988 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31235877 | 0.90 | NPY1R (0.52) | NPY2RNPY4RNPY5RNPY1RMAPK8 | |
| SCHEMBL30429358 | 0.89 | NPY2R (0.59) | NPY2RNPY4RNPY5RNPY1RMAPK8 | |
| SCHEMBL30338867 | 0.88 | MAPK8 (0.53) | NPY2RNPY4RNPY5RNPY1RMAPK8 | |
| SCHEMBL30410387 | 0.87 | NTSR2 (0.53) | MAPK8MAPK9MAPK10NTSR2NTSR1 | |
| SCHEMBL31307290 | 0.86 | EP300 (0.53) | NPY2RNPY4RNPY5RNPY1RMAPK8 | |
| SCHEMBL30576900 | 0.85 | NPY2R (0.59) | NPY2RNPY4RNPY5RNPY1RMAPK8 | |
| SCHEMBL30495689 | 0.85 | NPY2R (0.57) | NPY2RNPY4RNPY5RNPY1RMAPK8 | |
| SCHEMBL30512672 | 0.85 | MAPK8 (0.53) | NPY2RNPY4RNPY5RNPY1RMAPK8 | |
| SCHEMBL30603414 | 0.85 | XIAP (0.52) | NTSR2NTSR1SORT1XIAP | |
| SCHEMBL29776766 | 0.85 | MAPK8 (0.58) | MAPK8MAPK9MAPK10NTSR2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002014352-A9 | THERAPEUTIC COMPOUNDS FOR OVARIAN CANCER | GENZYME CORP (US) | 2004-03-04 | — | — | WO | disclosed |