Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 7/20 | 0.52 |
| ▸ | NPY2R | P49146 | 7/20 | 0.50 |
| ▸ | NPY4R | P50391 | 7/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 4/20 | 0.50 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | NMUR2 | Q9GZQ4 | 3/20 | 0.47 |
| ▸ | NMUR1 | Q9HB89 | 3/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30338867 | 0.91 | MAPK8 (0.53) | NPY1RNPY2RNPY4RNPY5RMAPK8 | |
| SCHEMBL8365216 | 0.90 | NPY2R (0.50) | NPY1RNPY2RNPY4RNPY5RNTSR1 | |
| SCHEMBL30442394 | 0.89 | APLNR (0.47) | NPY1RNPY2RNPY4RNPY5RMAPK8 | |
| SCHEMBL31657668 | 0.89 | RAMP3 (0.48) | NTSR1NTSR2F2NMUR2NMUR1 | |
| SCHEMBL32677417 | 0.88 | CXCR4 (0.47) | NTSR1NTSR2NMUR2NMUR1SORT1 | |
| SCHEMBL32677398 | 0.88 | CXCR4 (0.47) | NTSR1NTSR2NMUR2NMUR1SORT1 | |
| SCHEMBL32677400 | 0.88 | CXCR4 (0.47) | NTSR1NTSR2NMUR2NMUR1SORT1 | |
| SCHEMBL31235876 | 0.88 | NTSR1 (0.48) | NPY1RNPY2RNPY4RNPY5RNTSR1 | |
| SCHEMBL31235878 | 0.88 | NTSR1 (0.48) | NPY1RNPY2RNPY4RNPY5RNTSR1 | |
| SCHEMBL30410387 | 0.87 | NTSR2 (0.53) | NTSR1NTSR2MAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240376517-A1 | GRANZYME B DETECTION | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2024-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240376517-A1 | GRANZYME B DETECTION | GZMB, CTSB, DNASE1L3 | NPY1R 1620/4885NPY2R 1821/4885NPY4R 1512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.