Nithiazide

Nithiazide

SCHEMBL836586

CCNC(=O)Nc1ncc([N+](=O)[O-])s1

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ATG4B Q9Y4P1 17/20 0.80
CDK2 P24941 2/20 0.67
GSK3A P49840 2/20 0.67
GSK3B P49841 2/20 0.67
DYRK1A Q13627 1/20 0.67
HIPK4 Q8NE63 1/20 0.67
CLK4 Q9HAZ1 1/20 0.67
LMNA P02545 2/20 0.64
RPS6KB1 P23443 1/20 0.63
CDK5 Q00535 1/20 0.63
AURKB Q96GD4 1/20 0.63
MEN1 O00255 1/20 0.61
NPC1 O15118 1/20 0.61
ALDH1A1 P00352 1/20 0.61
MAPT P10636 1/20 0.61
HTT P42858 1/20 0.61
RAB9A P51151 1/20 0.61
KMT2A Q03164 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18529261 0.89 ATG4B (1.00) ATG4BCDK2GSK3AGSK3BDYRK1A
SCHEMBL1394642 0.87 ATG4B (0.85) ATG4BCDK2GSK3AGSK3BDYRK1A
SCHEMBL3234255 0.84 ATG4B (0.68) ATG4BCDK2GSK3AGSK3BDYRK1A
SCHEMBL18529254 0.82 ATG4B (1.00) ATG4BCDK2GSK3AGSK3BDYRK1A
SCHEMBL18529262 0.82 ATG4B (1.00) ATG4BCDK2GSK3AGSK3BDYRK1A
SCHEMBL18529287 0.81 ATG4B (1.00) ATG4BCDK2GSK3AGSK3BDYRK1A
SCHEMBL14559624 0.81 ATG4B (0.74) ATG4BCDK2GSK3AGSK3BDYRK1A
SCHEMBL10152517 0.81 ATG4B (0.79) ATG4BCDK2GSK3AGSK3BDYRK1A
SCHEMBL3234242 0.81 ATG4B (0.67) ATG4BCDK2GSK3AGSK3BDYRK1A
Nithiamide SCHEMBL158858 0.80 NPC1 (0.63) ATG4BLMNAMEN1NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 406 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112616845-A Pesticide composition containing pyrazole formamide insecticide and application thereof 青岛滕润翔检测评价有限公司 2021-04-09 CN claimed
CN-110461159-A Fungicidal compositions SYNGENTA PARTICIPATIONS AG 2019-11-15 CN claimed
CN-110300521-A FUNGICIDAL COMPOSITIONS 先正达参股股份有限公司 2019-10-01 CN claimed
CN-105745201-B 1-aryl-3-alkylpyrazole insecticides FMC公司 2019-08-20 CN claimed
CN-109890208-A FUNGICIDAL COMPOSITIONS 先正达参股股份有限公司 2019-06-14 CN claimed
CN-109890807-A The bicyclic azoles pesticide of heterocyclic substituted FMC 公司 2019-06-14 CN claimed
CN-108779092-A nematicidal heterocyclic amides 杜邦公司 2018-11-09 CN claimed
CN-108699031-A Heterocyclic substituted bicyclic azole insecticides FMC公司 2018-10-23 CN claimed
CN-108473508-A Heterocyclic substituted bicyclic azole insecticides FMC公司 2018-08-31 CN claimed
CN-108135170-A Fungicidal composition 先正达参股股份有限公司 2018-06-08 CN claimed
CN-102574815-A Mesoionic pesticides DU PONT 2012-07-11 CN claimed
CN-102413693-A Nematocidal sulfonamides DU PONT 2012-04-11 CN claimed
CN-102227166-A Pesticidal compositions comprising tetrazolyloxime derivatives and fungicidal or insecticidal active substances BAYER CROPSCIENCE SA 2011-10-26 CN claimed
CN-101977501-A Pesticidal compositions comprising tetrazolyloxime derivatives and fungicidal or insecticidal active substances BAYER CROPSCIENCE AG 2011-02-16 CN claimed
CN-101939302-A Mesoionic insecticides DU PONT 2011-01-05 CN claimed
CN-101815706-A isoxazoline insecticides DU PONT 2010-08-25 CN claimed
CN-101809004-A Naphthalene isoxazoline compounds for control of invertebrate pests DU PONT 2010-08-18 CN claimed
CN-101765592-A Naphthalene isoxazoline invertebrate pest control agents DU PONT 2010-06-30 CN claimed
CN-101646349-A Liquid formulations of carboxamide arthropodicides PONT US DU 2010-02-10 CN claimed
CN-101460533-A Reverse phase microcapsules for active ingredients, simplified preparation method thereof and combination formulations WDG-CS, ZC, EC-SC and CX GAT MICROENCAPSULATION AG (AT) 2009-06-17 CN claimed