Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366797 | 0.86 | — | — | |
| SCHEMBL10664837 | 0.81 | TSHR (0.36) | TSHRSLC6A2SLC6A4BLMSLC6A3 | |
| SCHEMBL11869933 | 0.78 | ALDH1A1 (0.42) | TSHRMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6762246 | 0.76 | TSHR (0.42) | TSHRBLMMEN1KMT2AALDH1A1 | |
| SCHEMBL1988202 | 0.75 | ALDH1A1 (0.50) | TSHRALDH1A1FGFR4SMN1; SMN2MAPT | |
| SCHEMBL6557587 | 0.75 | ALDH1A1 (0.50) | TSHRNFKB1ALDH1A1FGFR4SMN1; SMN2 | |
| SCHEMBL11662426 | 0.75 | TSHR (0.43) | TSHRNFKB1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2911988 | 0.74 | — | — | |
| SCHEMBL28987308 | 0.74 | GSR (0.53) | TSHRBLMNFKB1CYP2C19KMT2A | |
| SCHEMBL10657947 | 0.74 | GSR (0.35) | TSHRSLC6A2SLC6A4BLMSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856015-B1 | NEW POLYACRYLAMIDE MATRICES IN ELECTROPHORETIC AND CHROMATOGRAPHIC TECHNIQUES | RIGHETTI PIER GIORGIO (IT) | 1999-12-08 | — | — | EP | claimed |