Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 19/20 | 0.78 |
| ▸ | RARB | P10826 | 9/20 | 0.78 |
| ▸ | RARG | P13631 | 8/20 | 0.78 |
| ▸ | RXRG | P48443 | 12/20 | 0.59 |
| ▸ | RXRB | P28702 | 10/20 | 0.59 |
| ▸ | RARA | P10276 | 4/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15886820 | 1.00 | RXRA (0.78) | RXRARARBRARGRXRGRXRB | |
| SCHEMBL727073 | 1.00 | RXRA (0.78) | RXRARARBRARGRXRGRXRB | |
| SCHEMBL8364736 | 1.00 | RXRA (0.78) | RXRARARBRARGRXRGRXRB | |
| SCHEMBL4895819 | 1.00 | RXRA (0.78) | RXRARARBRARGRXRGRXRB | |
| SCHEMBL4905159 | 1.00 | RXRA (0.78) | RXRARARBRARGRXRGRXRB | |
| SCHEMBL727074 | 1.00 | RXRA (0.78) | RXRARARBRARGRXRGRXRB | |
| SCHEMBL8361331 | 0.85 | RXRA (0.58) | RXRARARBRARGRXRGRXRB | |
| SCHEMBL8361333 | 0.85 | RXRA (0.58) | RXRARARBRARGRXRGRXRB | |
| SCHEMBL6862503 | 0.82 | RXRA (0.57) | RXRARARBRARGRXRGRXRB | |
| SCHEMBL6862497 | 0.82 | RXRA (0.57) | RXRARARBRARGRXRGRXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775103-B1 | RETINOIC ACID X-RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 1999-06-09 | — | — | EP | claimed |
| EP-0775103-B1 | RETINOIC ACID X-RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 1999-06-09 | — | — | EP | disclosed |