Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL836629 | 1.00 | NR3C1 (0.82) | NR3C1PGR | |
| SCHEMBL834373 | 0.93 | NR3C1 (0.82) | NR3C1PGR | |
| SCHEMBL833896 | 0.93 | NR3C1 (0.81) | NR3C1PGR | |
| SCHEMBL835893 | 0.93 | NR3C1 (0.81) | NR3C1PGR | |
| SCHEMBL13315341 | 0.92 | NR3C1 (0.84) | NR3C1PGR | |
| SCHEMBL836288 | 0.91 | NR3C1 (0.84) | NR3C1PGR | |
| SCHEMBL836287 | 0.91 | NR3C1 (0.84) | NR3C1PGR | |
| SCHEMBL835086 | 0.91 | NR3C1 (0.78) | NR3C1PGR | |
| SCHEMBL4218315 | 0.91 | NR3C1 (0.78) | NR3C1PGR | |
| SCHEMBL850639 | 0.91 | NR3C1 (0.78) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102169-B1 | INDAZOLYL AMIDE DERIVATIVES FOR THE TREATMENT OF GLUCOCORTICOID RECEPTOR MEDIATED DISORDERS | ASTRAZENECA AB (SE) | 2012-06-20 | — | — | EP | claimed |
| EP-2102169-B1 | INDAZOLYL AMIDE DERIVATIVES FOR THE TREATMENT OF GLUCOCORTICOID RECEPTOR MEDIATED DISORDERS | ASTRAZENECA AB (SE) | 2012-06-20 | — | — | EP | disclosed |
| US-8143290-B2 | Chemical compounds 572 | ASTRAZENECA AB (SE) | 2012-03-27 | — | — | US | disclosed |
| WO-2009142568-A1 | COMBINATION OF (A) GLUCOCORTICOID RECEPTOR MODULATOR AND (B) A B2-AGONIST | ASTRAZENECA AB (SE) | 2009-11-26 | — | — | WO | disclosed |