Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368861 | 0.87 | PTGS1 (0.50) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL3720936 | 0.86 | MAPK8 (0.50) | MAPTKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL29456313 | 0.86 | MAPK8 (0.50) | MAPTKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL14564395 | 0.84 | MAPT (0.51) | MAPTKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL3776134 | 0.83 | NAMPT (0.47) | MAPTKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL6717869 | 0.82 | MAPT (0.55) | MAPTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4049057 | 0.81 | GRIK1 (0.55) | MAPTKDM4EMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL29456293 | 0.80 | MAPK9 (0.52) | KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL3783019 | 0.80 | MAPK9 (0.52) | KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL13100002 | 0.80 | KDM4E (0.49) | MAPTKDM4EALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958924-A | HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS, RESTENOSIS, ANTICOALUGANTS, RESPIRATORY SYSTEM DISORDERS | SYNTHELABO (FR) | 1999-09-28 | — | — | US | disclosed |