SCHEMBL4049057

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20710538	0.89	MAPT (0.67)	GRIK1GRIK2NPSR1MAPTSMN1; SMN2
	SCHEMBL28979220	0.83	PDE5A (0.62)	MAPTSMN1; SMN2KMT2AKDM4EPOLB
	SCHEMBL2797929	0.83	KMT2A (0.48)	GRIK1GRIK2NPSR1MAPTSMN1; SMN2
	SCHEMBL8522381	0.83	KMT2A (0.48)	GRIK1GRIK2SMN1; SMN2KMT2AMTNR1A
	SCHEMBL8368861	0.82	PTGS1 (0.50)	SMN1; SMN2KMT2AKDM4E
	SCHEMBL8366395	0.81	MAPT (0.52)	MAPTSMN1; SMN2TDP1KMT2AMTNR1A
	SCHEMBL2799788	0.79	KMT2A (0.44)	GRIK1GRIK2MAPTSMN1; SMN2KMT2A
	SCHEMBL6074279	0.78	BRPF1 (0.59)	MAPTSMN1; SMN2KMT2AMTNR1AMTNR1B
	SCHEMBL9310207	0.78	BTK (0.52)	MAPTRXFP1KMT2ACDK4CCND1
	SCHEMBL9499012	0.77	KDM4E (0.50)	MAPTSMN1; SMN2KMT2AMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.