Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL31281131 | 1.00 | NFKB1 (0.40) | — | |
| Ethylenediamine SCHEMBL29404108 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL1436759 | 0.86 | NFKB1 (0.40) | — | |
| Ethylenediamine SCHEMBL17223141 | 0.86 | NFKB1 (0.40) | — | |
| Ethylenediamine SCHEMBL2168954 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL2169963 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL2170654 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL10537063 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL2171867 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL11585256 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874137-A | Organometallic solvent seaming of cellulosic materials | KRAFT FOODS, INC. (US) | 1999-02-23 | — | — | US | claimed |
| US-5690777-A | Seamed cellulosic materials using organometallic solvents | KRAFT FOODS, INC. (US) | 1997-11-25 | — | — | US | claimed |
| US-5658414-A | Organometallic solvent seaming of cellulosic materials | KRAFT FOODS, INC. (US) | 1997-08-19 | — | — | US | claimed |
| EP-0779324-A2 | Organometallic solvent seaming of cellulosic materials | KRAFT FOODS, INC. (US) | 1997-06-18 | — | — | EP | claimed |
| EP-0729704-A1 | Seamed cellulosic materials using organometallic solvents | KRAFT FOODS, INC. (US) | 1996-09-04 | — | — | EP | claimed |