Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 2/20 | 0.49 |
| ▸ | MARS1 | P56192 | 5/20 | 0.47 |
| ▸ | CNR2 | P34972 | 6/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368933 | 0.93 | RPA1 (0.51) | RPA1MARS1CNR2CNR1PPP1CA | |
| SCHEMBL8368110 | 0.91 | CNR2 (0.49) | RPA1MARS1CNR2CNR1SMPD1 | |
| SCHEMBL5902998 | 0.88 | CNR2 (0.57) | RPA1MARS1CNR2CNR1PPP1CA | |
| Hydrochloric Acid SCHEMBL8369717 | 0.86 | CNR2 (0.56) | RPA1MARS1CNR2CNR1PPP1CA | |
| SCHEMBL8369654 | 0.84 | MARS1 (0.49) | RPA1MARS1CNR2CNR1PPP1CA | |
| SCHEMBL8369248 | 0.84 | CNR2 (0.50) | RPA1MARS1CNR2CNR1 | |
| SCHEMBL8369874 | 0.81 | RPA1 (0.61) | RPA1MARS1PPP1CASMN1; SMN2P2RY14 | |
| SCHEMBL8369153 | 0.80 | MARS1 (0.53) | RPA1MARS1CNR2CNR1PPP1CA | |
| SCHEMBL8366415 | 0.80 | MARS1 (0.53) | RPA1MARS1CNR2CNR1PPP1CA | |
| SCHEMBL8369101 | 0.79 | RPA1 (0.61) | RPA1MARS1CNR2CNR1PPP1CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |