Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 5/20 | 0.65 |
| ▸ | PYGM | P11217 | 3/20 | 0.46 |
| ▸ | TYMP | P19971 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CDA | P32320 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TK1 | P04183 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.43 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366490 | 1.00 | TK2 (0.65) | TK2PYGMTYMPMAPTCDA | |
| SCHEMBL8333791 | 0.80 | TK2 (0.60) | TK2PYGMMAPTCDACYP1A2 | |
| SCHEMBL27773751 | 0.80 | TK2 (0.60) | TK2PYGMMAPTCDACYP1A2 | |
| SCHEMBL6753689 | 0.80 | TK2 (0.60) | TK2PYGMMAPTCDACYP1A2 | |
| SCHEMBL11665141 | 0.79 | MAPT (0.48) | PYGMTYMPMAPTCDABLM | |
| Sorivudine SCHEMBL5511785 | 0.79 | TK2 (1.00) | TK2PYGMCYP1A2CYP3A4TSHR | |
| Sorivudine SCHEMBL2584824 | 0.79 | TK2 (1.00) | TK2PYGMCYP1A2CYP3A4TSHR | |
| Sorivudine SCHEMBL1981704 | 0.79 | TK2 (1.00) | TK2PYGMCYP1A2CYP3A4TSHR | |
| Sorivudine SCHEMBL3503357 | 0.79 | TK2 (1.00) | TK2PYGMCYP1A2CYP3A4TSHR | |
| Sorivudine SCHEMBL1981707 | 0.79 | TK2 (1.00) | TK2PYGMCYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891374-A4 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | UNIV COLUMBIA (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0891374-A1 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | The Trustees of Columbia University in the City of New York (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997027208-A1 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1997-07-31 | — | — | WO | disclosed |