Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 5/20 | 0.60 |
| ▸ | PYGM | P11217 | 3/20 | 0.44 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.43 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TK1 | P04183 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CDA | P32320 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6753689 | 1.00 | TK2 (0.60) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL27773751 | 1.00 | TK2 (0.60) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL26970055 | 0.82 | PYGM (0.53) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL12987792 | 0.80 | TK1 (0.60) | TK2CYP1A2CYP3A4TSHRTK1 | |
| SCHEMBL2056570 | 0.80 | SLC28A1 (0.47) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL8366489 | 0.80 | TK2 (0.65) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL8366490 | 0.80 | TK2 (0.65) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL8536800 | 0.79 | PYGM (0.46) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL15689564 | 0.79 | PYGM (0.46) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL8536802 | 0.79 | PYGM (0.46) | TK2PYGMSLC28A1SLC28A2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934333-A4 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | UNIV COLUMBIA (US) | 1999-11-03 | — | — | EP | disclosed |
| EP-0804547-A4 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | UNIV COLUMBIA (US) | 1999-11-03 | — | — | EP | disclosed |
| EP-0934333-A1 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | The Trustees of Columbia University in the City of New York (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998004576-A1 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1998-02-05 | — | — | WO | disclosed |
| EP-0804547-A1 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | The Trustees of Columbia University in the City of New York (US) | 1997-11-05 | — | — | EP | disclosed |
| EP-0475992-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-03-25 | — | — | EP | disclosed |
| WO-1990015064-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-12-13 | — | — | WO | disclosed |