Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364668 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL8366718 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2TDP1HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL8366720 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL8369714 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL27433542 | 0.83 | MARS1 (0.45) | SMN1; SMN2TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL27537043 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL8369807 | 0.81 | HDAC3 (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8369096 | 0.76 | MAPT (0.58) | SMN1; SMN2TDP1HDAC1MAPTMEN1 | |
| SCHEMBL8366688 | 0.74 | P2RY14 (0.56) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL25210030 | 0.74 | CHEK1 (0.53) | SMN1; SMN2TDP1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |