Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 8/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 8/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8367566 | 0.89 | GRIA1 (0.64) | GRIA1SMN1; SMN2 | |
| SCHEMBL678000 | 0.83 | GRIA1 (1.00) | GRIA1SMN1; SMN2 | |
| SCHEMBL29542563 | 0.83 | GRIA1 (1.00) | GRIA1SMN1; SMN2 | |
| SCHEMBL8314975 | 0.83 | GRIA1 (0.82) | GRIA1 | |
| SCHEMBL8368416 | 0.82 | GRIA1 (0.62) | GRIA1GRM5 | |
| SCHEMBL8368414 | 0.79 | GRIA1 (0.64) | GRIA1 | |
| SCHEMBL8367555 | 0.78 | GRIA1 (0.80) | GRIA1 | |
| SCHEMBL8367567 | 0.78 | GRIA1 (0.75) | GRIA1 | |
| SCHEMBL31562972 | 0.78 | GRIA1 (0.84) | GRIA1 | |
| SCHEMBL12049626 | 0.78 | GRIA1 (0.84) | GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799913-B2 | Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses | CORTEX PHARMACEUTICALS, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| US-7799913-B2 | Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses | CORTEX PHARMACEUTICALS, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| WO-2003045315-A2 | CARBONYLBENZOXAZINE COMPOUNDS FOR ENHANCING GLUTAMATERGIC SYNAPTIC RESPONSES | CORTEX PHARMACEUTICALS, INC. (US) | 2003-06-05 | — | — | WO | disclosed |