Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 19/20 | 0.77 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8365107 | 0.87 | SLC6A9 (1.00) | SLC6A9 | |
| SCHEMBL5240894 | 0.87 | SLC6A9 (1.00) | SLC6A9 | |
| SCHEMBL5242085 | 0.86 | SLC6A9 (1.00) | SLC6A9 | |
| SCHEMBL5279660 | 0.86 | SLC6A9 (1.00) | SLC6A9 | |
| SCHEMBL5968436 | 0.84 | SLC6A9 (0.81) | SLC6A9 | |
| SCHEMBL14381241 | 0.79 | SLC6A9 (0.74) | SLC6A9HTR7 | |
| SCHEMBL5240941 | 0.79 | SLC6A9 (0.50) | SLC6A9HTR7 | |
| SCHEMBL14382102 | 0.79 | SLC6A9 (1.00) | SLC6A9HTR7 | |
| SCHEMBL14382140 | 0.79 | SLC6A9 (1.00) | SLC6A9HTR7 | |
| SCHEMBL14381969 | 0.78 | GBA1 (0.66) | SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003055478-A1 | GLYT1 TRANSPORTER INHIBITORS AND USES THEREOF IN TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-07-10 | — | — | WO | disclosed |