Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3681350 | 1.00 | KDM4E (0.62) | KDM4EMAPTALDH1A1TSHRHPGD | |
| SCHEMBL3681348 | 1.00 | KDM4E (0.62) | KDM4EMAPTALDH1A1TSHRHPGD | |
| SCHEMBL8369833 | 0.88 | ALDH1A1 (0.63) | KDM4EMAPTALDH1A1TSHRMEN1 | |
| SCHEMBL8369834 | 0.88 | ALDH1A1 (0.63) | KDM4EMAPTALDH1A1TSHRMEN1 | |
| SCHEMBL13980028 | 0.84 | MAPT (0.47) | KDM4EMAPTALDH1A1TSHRHPGD | |
| SCHEMBL4003545 | 0.82 | MAPT (0.46) | KDM4EMAPTALDH1A1TSHRHPGD | |
| SCHEMBL4003542 | 0.82 | MAPT (0.46) | KDM4EMAPTALDH1A1TSHRHPGD | |
| SCHEMBL8369822 | 0.82 | ALDH1A1 (0.73) | KDM4EMAPTALDH1A1TSHRHPGD | |
| SCHEMBL8369820 | 0.82 | ALDH1A1 (0.73) | KDM4EMAPTALDH1A1TSHRHPGD | |
| SCHEMBL3338689 | 0.82 | HPGD (0.44) | KDM4EMAPTALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |