Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1614082 | 0.75 | SMN1; SMN2 (0.55) | HSD17B10GAAALDH1A1KDM4EHPGD | |
| SCHEMBL10618516 | 0.70 | HSD17B10 (0.53) | HSD17B10GAAALDH1A1KDM4EHPGD | |
| SCHEMBL17844514 | 0.69 | PTGS1 (0.40) | PTGS2PTGS1PDE3AHSD17B10ALDH1A1 | |
| SCHEMBL151820 | 0.67 | HSD17B10 (0.57) | HSD17B10GAAALDH1A1KDM4EMEN1 | |
| SCHEMBL30969123 | 0.67 | HSD17B10 (0.57) | HSD17B10GAAALDH1A1KDM4EMEN1 | |
| SCHEMBL11739523 | 0.66 | GAA (0.63) | PTGS1HSD17B10GAAALDH1A1KDM4E | |
| SCHEMBL9786071 | 0.65 | HSD17B10 (0.54) | HSD17B10GAAALDH1A1KDM4EHPGD | |
| SCHEMBL28658763 | 0.65 | HSD17B10 (0.50) | HSD17B10GAAALDH1A1KDM4EHPGD | |
| SCHEMBL149945 | 0.64 | HSD17B10 (0.53) | HSD17B10GAAALDH1A1KDM4EHPGD | |
| SCHEMBL3328675 | 0.64 | AKR1B1 (0.50) | PTGS2PTGS1HSD17B10GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0954596-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES | PHYTON, INC. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1997044476-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON, INC. (US) | 1997-11-27 | — | — | WO | disclosed |