Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 9/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6643730 | 0.86 | BDKRB2 (0.56) | BDKRB2 | |
| SCHEMBL6578778 | 0.84 | BDKRB2 (0.62) | BDKRB2 | |
| SCHEMBL6642830 | 0.84 | BDKRB2 (0.63) | BDKRB2 | |
| SCHEMBL8367538 | 0.83 | BDKRB2 (0.49) | BDKRB2 | |
| SCHEMBL8367539 | 0.83 | GAA (0.49) | BDKRB2GAATDP1 | |
| SCHEMBL8364193 | 0.82 | BDKRB2 (0.54) | BDKRB2GAATDP1 | |
| SCHEMBL6580633 | 0.77 | BDKRB2 (0.55) | BDKRB2 | |
| SCHEMBL8367611 | 0.76 | BDKRB2 (0.57) | BDKRB2 | |
| SCHEMBL8361717 | 0.76 | BDKRB2 (0.63) | BDKRB2 | |
| SCHEMBL6642693 | 0.76 | BDKRB2 (0.58) | BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994368-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0807105-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996013485-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-09 | — | — | WO | disclosed |