Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10825016 | 0.87 | GPR84 (0.49) | GPR84TRPV1HSD17B3ESR1S1PR2 | |
| SCHEMBL604072 | 0.84 | ESR1 (0.47) | TRPV1HSD17B3ESR1S1PR2S1PR1 | |
| SCHEMBL8954863 | 0.80 | GPR84 (0.39) | GPR84MMP9MMP2MMP12LMNA | |
| SCHEMBL3724690 | 0.78 | ESR1 (0.59) | HSD17B3ESR1ESR2LMNACYP3A4 | |
| SCHEMBL3879432 | 0.78 | ESR1 (0.59) | HSD17B3ESR1ESR2LMNACYP3A4 | |
| SCHEMBL3872457 | 0.78 | ESR1 (0.59) | HSD17B3ESR1ESR2LMNACYP3A4 | |
| SCHEMBL9354788 | 0.77 | ESR1 (0.53) | TRPV1HSD17B3ESR1ESR2NR1I2 | |
| SCHEMBL17260545 | 0.77 | ESR1 (0.53) | TRPV1HSD17B3ESR1ESR2NR1I2 | |
| SCHEMBL3643220 | 0.77 | ESR1 (0.53) | TRPV1HSD17B3ESR1ESR2NR1I2 | |
| SCHEMBL5046756 | 0.77 | ESR1 (0.53) | TRPV1HSD17B3ESR1ESR2NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052502-A1 | SKIN CARE COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1999-10-21 | — | — | WO | disclosed |