Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GALR2 | O43603 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810412 | 0.84 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2POLBLMNAGALR2 | |
| SCHEMBL4306866 | 0.81 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2POLBLMNAGALR2 | |
| SCHEMBL810673 | 0.81 | CUL4A (0.45) | ALDH1A1SMN1; SMN2POLBLMNAGALR2 | |
| SCHEMBL3274429 | 0.81 | KMT2A (0.41) | ALDH1A1SMN1; SMN2POLBLMNAGALR2 | |
| SCHEMBL18306134 | 0.81 | CUL4A (0.45) | ALDH1A1SMN1; SMN2POLBLMNAGALR2 | |
| SCHEMBL24453320 | 0.81 | POLB (0.45) | ALDH1A1SMN1; SMN2POLBLMNAGALR2 | |
| SCHEMBL31047098 | 0.81 | CUL4A (0.45) | ALDH1A1SMN1; SMN2POLBLMNAGALR2 | |
| SCHEMBL10257277 | 0.81 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2POLBLMNAGALR2 | |
| SCHEMBL962620 | 0.80 | NPC1 (0.44) | ALDH1A1SMN1; SMN2POLBLMNAGALR2 | |
| SCHEMBL4090654 | 0.77 | POLB (0.46) | ALDH1A1SMN1; SMN2POLBLMNAGALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638566-B1 | 5-Aminoflavone derivatives, their preparation and their use as antibacterial, anti-estrogenic and/or antitumor agent | KYOWA HAKKO KOGYO KK (JP) | 1999-01-07 | — | — | EP | disclosed |
| US-5539112-A | 5-aminoflavone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0638566-A1 | 5-Aminoflavone derivatives, their preparation and their use as antibacterial, anti-estrogenic and/or antitumor agent | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |