SCHEMBL8367828

SCHEMBL8367828

Cc1cc(N(C)C)c2cccc(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)C=Cc4ccc(NC(=O)c5ccncc5)cc4)c3Cl)c2n1

nearest known ligand 0.99

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 20/20 0.99

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8364323 0.97 BDKRB2 (1.00) BDKRB2
SCHEMBL8364324 0.97 BDKRB2 (1.00) BDKRB2
SCHEMBL8365938 0.93 BDKRB2 (0.85) BDKRB2
SCHEMBL8365941 0.93 BDKRB2 (0.85) BDKRB2
SCHEMBL8367335 0.93 BDKRB2 (0.88) BDKRB2
SCHEMBL8367334 0.93 BDKRB2 (0.88) BDKRB2
SCHEMBL6964174 0.91 BDKRB2 (1.00) BDKRB2
SCHEMBL6962519 0.90 BDKRB2 (0.97) BDKRB2
SCHEMBL6962529 0.90 BDKRB2 (0.97) BDKRB2
SCHEMBL7748412 0.90 BDKRB2 (0.95) BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5994368-A ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANALGESICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-11-30 US disclosed